Department of Clinical Pharmacy & Pharmacology

1.0 Background

The department started as the Unit of Pharmacology and Therapeutics in 2008 at the School of Pharmacy of Muhimbili University of Health and Allied Sciences (MUHAS). During this period, the Unit was housed in the Department of Pharmacognosy in the School of Pharmacy. As a result of increased number of faculty and postgraduate students, the Unit was upgraded to a Department in 2015.

2.0 Human Resources

The Department of Clinical Pharmacy and Pharmacology is comprised of myriad of fulltime faculty including 2 Tutorial Assistants, 3 Assistant Lectures, 1 Associate Professor and 1 Full Professor. Two Tutorial Assistants and One Assistant Lecture are currently enrolled in Master and PhD programs, respectively. Two Assistant Lectures are expected to enroll for PhD training in the next academic year of 2017/2018.  Currently, there is one part time Professor from People`s Republic of China who is part of the teaching staff.

3.0 Teaching and Capacity Building

3.1 Undergraduate Program

The department aims at providing excellence in undergraduate and postgraduate teaching in basic pharmacology, clinical pharmacology and therapeutics. Teaching is aiming at imparting graduates with skills in patient care services to collaboratively work with other clinical care team members in the health facilities. The focus is for trained pharmacists to be able to detect and report medication errors and manage drug therapy. The competency-based curricular for undergraduate in the department covers three years of study i.e. second year (semester 3), third year (semester 5) and fourth year (semester 7). In semesters 3 and 5, students are taught basic pharmacology. In semester 7, students covers therapeutics of the major diseases conditions. During semester 7, students spends much time in the wards in which they participate in ward rounds, review files and make presentations.

The department has gained experience in conducting clinical rotations for both undergraduate and postgraduate students. In doing so, the members of the departments and students participate in multidisciplinary ward rounds at Muhimbili National Hospital (MNH), Jakaya Kikwete Cardiac Institute (JKCI) and Ocean Road Cancer Institute. The department heads the Unit of Clinical Pharmacy at the newly established MUHAS Academic Medical Center (MAMC) at Mloganzila Campus. Currently the department is developing Standard Operating Procedures for Clinical Pharmacy in MAMC. The Head of Department is a member of the University-wide Clinical Committee for MAMC which is tasked to oversee all operationalization plans for clinical services including teaching and patient care at MAMC.

3.2 Postgraduate program

The department is hosting one Master Program of Hospital and Clinical Pharmacy. This is a 2-year program (semesters 1-4) in which trainees spend much of the time in the wards. Students undertaking this program are exposed in supervised and unsupervised hospital major and minor ward rounds in a team with other medical personnel including medical doctors and nurses. This program is the first master of Pharmacy program in Hospital and Clinical Pharmacy in Tanzania. The major subjects that are covered in this postgraduate curriculum include: Therapeutics, Microbiology, Epidemiology and Data analysis, Clinical Pharmacokinetics, Therapeutics Based ward rounds and Research Methodology. In semester 2, trainees are required to developed research proposals and start data collection, specifically from hospitals. In semester 4, trainees are required to produce and defend dissertations before they can graduate. The program is among the leading programs in enrolling students at the School of Pharmacy every year.

4.0 Research and Training

4.1 Research Areas

The department is dedicated in conducting both basic and clinical researches in the following areas:

               i.   Clinical pharmacokinetics and pharmacogenetics of antimalarial and antiretroviral drugs

      ii.  Bioequivalence and bioavailability studies

     iii.  Treatment adherence studies and rational use of medicines

     iv.  Pharmacovigilance studies

      v.  Therapeutic drug monitoring studies

     vi.  Clinical trials

    vii.  Antimalarial treatment efficacy studies in pregnant women

  viii.  Bioanalytics

4.2 Research Capacity and Training

Since its establishment as the Unit in 2008, the department has been part of the MUHAS-Sida projects. From the year 2011, the department has supervised more than 10 Masters Dissertations and 6 PhDs.  Currently, there are 3 PhD students and 4 Master degree students being supervised in the department.   

The two professors in the department are recipients of Sida-MUHAS research grant for the period of July 2015 to June 2020. In this research grant, 2 members of the department are being trained at Masters level and 1 at PhD level. The program is also training at PhD level one member of staff from Department of Pharmaceutics (School of Pharmacy), and another one from the Department of Clinical Pharmacology (School of Medicine). All these trainees are supervised by senior members of the department.

For Masters and PhD training, the department is collaborating with Karolinska Institute, in Sweden.  Among the 3 PhD students in the Sida-MUHAS program, 2 are registered at Karolinska Institute under sandwich program and are co-supervised by faculty from MUHAS and Karolinska Institute.

The department has a MUHAS-Sida Bioanalytical Laboratory which provides space and facilities for training Masters and PhD students in bioanalytical studies of various drugs in the country. The laboratory is one among the few laboratories in the country with capacity to conduct determination of drugs in biological samples such as whole blood, dried blood spots, urine, serum, plasma and others. At the moment, the Department is building its capacity to conduct Therapeutic drug Monitoring. The department has expertise in designing and conducting pharmacokinetics, drug safety and efficacy studies in Africa.

5.0 Short Courses

Through MUHAS-Sida research grant, the department has developed one short course in Clinical Pharmacokinetics and Drug Metabolism. It is also developing a course in Pharmaceutical Clinical Care which is designed to build competences of graduate pharmacists for conducting clinical rotations and pharmacological patient care.

6.0 Members of the Department and Their Academic Profiles

Currently, the department has a total of 7 permanently employed faculty as summarized below:

  1. Professor Appolinary Kamuhabwa (Bpharm, UDSM; Mpharm, KU-Leuven-Belgium; PhD, KU-Leuven-Belgium; Postdoc KU-Leuven-Belgium). Professor Kamuhabwa is a Full Professor and currently saves as the Deputy Vice Chancellor responsible for Planning, Finance and Administration at MUHAS.
  2. Professor Omary Minzi (Mpharm, Pyatigorsk USSR; MSc, VUB; PhD, KI/UDSM). Professor Minzi is an Associate Professor, and currently saves as the Head of Department.
  3. Ms. Ritah Mutagonda (Bpharm, MUHAS; Mpharm, MUHAS; On PhD program at MUHAS). Ms. Mutagonda is an Assistant Lecturer. She is on PhD training expecting to graduate in 2018.
  4. Mr. Alphonce Marealle (BPharm, MUHAS; Mpharm MUHAS). Mr. Marealle is an Assistant Lecturer.
  5. Mr. Hamu Mlyuka (Bpharm, MUHAS; MPharm, MUHA). Mr. Mlyuka is an Assistant Lecturer.
  6. Mr. Kilonzi Manase (BPharm, MUHAS; on MPharm training at MUHAS). Mr. Manase is a Tutorial Assistant. He is currently registered for Masters training at MUHAS.
  1. Mr. Wigilya Mikomangwa (BPharm, MUHAS; on MPharm training at MUHAS). Mr. Mikomangwa is a Tutorial Assistant. He is currently registered for Masters training at MUHAS.

 

7.0 Published Papers

The department has published more than 90 publications in peer reviewed journals. Most of these papers can be accessed at `www.pubmed.com`.

 

Contact US

SCHOOL OF PHARMACY
P.O. Box 65013
Dar es Salaam
Tel: Direct: +255-22-2151680, Tel: +255 22 2150302-6 (Ext. 1008 Dean, 1276 OMS)
Fax: +255-022-2150465
E-Mail dspha@muhas.ac.tz